Helicobacter pylori (HP) is a bacteria that parasitizes in the human stomach, and it is also the main factor leading to chronic active gastritis, gastric ulcer and duodenal ulcer.
HP can spread through:
Mouth to mouth (shared tableware, water cup, shared meals, etc.)
Stomach mouth (reflux from stomach to mouth)
Feces mouth (feces pollute water or food)
High infection and familial aggregation in children are the significant characteristics of Helicobacter pylori infection, and family transmission is the main route of Helicobacter pylori infection.
Because HP infection usually has no clinical symptoms in the early stage, it is often easy to be ignored. At present, domestic and foreign studies generally believe that HP infection is the main carcinogen of gastric cancer, and clinical investigations in recent years have shown that China is a big country of HP infection, the infection rate of Helicobacter pylori in the general population is as high as 50%-80%, with a very high infection rate. Therefore, the popularization of routine HP infection detection has become an important measure for the clinical prevention and treatment of gastric cancer in China.
HP testing is recommended if:
| Peptic ulcer (regardless of activity and history of complications) | Gastric MALT lymphoma |
| Chronic gastritis with dyspepsia | Chronic gastritis with atrophy and erosion of gastric mucosa |
| Early gastric tumors have been treated with endoscopic resection or surgical subtotal gastrectomy | Family history of gastric cancer |
Urease test, serum enzyme-linked immunosorbent assay (ELISA) and breath test are the main methods used in clinical detection of HP infection. The breath test is safe, rapid, effective and non-invasive, and foreign studies believe that this method can be used as an effective examination method for follow-up observation of treatment effect and epidemiological investigation.
Carbon 13 breath test principle: As long as you breathe into the instrument, you can check whether you have Helicobacter pylori infection. Because HP bacteria have urease, when it encounter the swallowed carbon 13 labeled urea (13C-urea) in the stomach, it will break it down into carbon 13 carrying carbon dioxide (C13O2), C13O2 is absorbed in the gastrointestinal tract, reaches the lung and exhaled with exhalation. If we collect the exhaled breath and measure the C13 labeled C13O2 in it, we can accurately prove the presence or absence of HP infection.
Normal people do not have HP, 13C-urea does not break down, 13C-urea is excreted through the urinary system, and there is no C13O2 in the exhaled gas. And people with H. pylori infection, they have H. pylori in their body, which breaks down 13C-urea, so they have C13O2 in their breath.
Pini Test carries out the carbon 13 breath detection of gastric Helicobacter pylori to help patients obtain test results safely, effectively, non-invasive and quickly, and to provide customers with high-quality testing and thoughtful service.
